Hydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats

Asami Matsumoto, Daniel M. Rolston, Junhwan Kim, Junichi Sasaki, Kei Hayashida, Kentaro Oka, Koichiro Homma, Koichiro Shinozaki, Lance B. Becker, Mitsuaki Nishikimi, Motomichi Takahashi, Muhammad Shoaib, Rishabh C. Choudhary, Ryosuke Takegawa, Santiago J. Miyara, Shuhei Eguchi, Tadashi Ariyoshi, Tai Yin, Tomoaki Aoki, Yusuke Endo

Background: Despite the benefits of extracorporeal cardiopulmonary resuscitation (ECPR) in cohorts of selected patients with cardiac arrest (CA), extracorporeal membrane oxygenation (ECMO) includes an artificial...

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A drug co-delivery platform made of magnesium-based micromotors enhances combination therapy for hepatoma carcinoma cells

Bohan Wang, Jing Li, Miao Feng, Qingtao Song, Wenjuan Liu, Xiaoyong Ding, Yilin Liu, Zhongwei Gu

Combination therapy is an emerging strategy to overcome multidrug resistance (MDR) in hepatocellular carcinoma (HCC) chemotherapy treatment. However, the passive diffusion in traditional delivery systems...

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Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice

Chuang Zhu, Hongli Yan, Li Yang, Lihua Song, Xinwen Ding, Yao Zhang

Purpose: Oxidative damage and intestinal flora dysbiosis play important roles in the progression of chronic ulcerative colitis (UC). This study explored the effect and mechanism...

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Effect of hydrogen/oxygen therapy for ordinary COVID-19 patients: a propensity-score matched case-control study

Jindong Shi, Junhong Jiang, Kai Wang, Nanshan Zhong, Weijie Guan, Xiaohua Chen, Xiaoping Tan, Xiaoting Ren, Xinyu Li, Xu Zou, Yingying Zeng, Zeguang Zheng, Zhijun Jie

Background: Hydrogen/oxygen therapy contribute to ameliorate dyspnea and disease progression in patients with respiratory diseases. Therefore, we hypothesized that hydrogen/oxygen therapy for ordinary coronavirus disease...

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Response of Escherichia coli to hydrogen nanobubbles: an in vitro evaluation using synchrotron infrared spectroscopy

Bin Li, Jie Cheng, Jin Zheng, Jinfang Lu, Jun Hu, Junhong Lu, Xueling Li, Yadi Wang

Hydrogen (H2)-rich water, an apparent source of molecular H2, is an emerging functional drink with many purported benefits for human health (Yang et al., 2020;...

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In vitro fermentation properties of magnesium hydride and related modulation effects on broiler cecal microbiome and metabolome

Haiyan Yang, He Zhu, Heng Hu, Weijiang Zheng, Wen Yao

Magnesium hydride (MGH), a highly promising hydrogen-producing substance/additive for hydrogen production through its hydrolysis reaction, has the potential to enhance broiler production. However, before incorporating...

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Abstract 556: Protective Effect of a Hydrogen-Rich Preservation Solution During Cold Ischemia in Rat Lung Transplantation

A. Aoyama, A. Takahagi, F. Gochi, H. Date, H. Kayawake, H. Motoyama, H. Yamagishi, J. Tokuno, M. Hamaji, M. Saito, R. Okabe, S. Hirano, S. Ueda, T. Chen-Yoshikawa

No abstract available Publish Year 2018 Country Japan Rank Positive Journal Journal of Heart and Lung Transplantation Primary Topic Lung Secondary TopicSurgery/Transplantation Model Rat Tertiary...

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Transcriptome analysis of hydrogen inhibits osteoclastogenesis of mouse bone marrow mononuclear cells

Hui Zeng, Wei Wang, Yong Liu, Yong Zeng

Hydrogen (H2) is a major biodegradation product of implanted magnesium (Mg) alloys that are commonly used in the healing of bone fractures. Our earlier study...

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Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death

Chao Meng, Huacheng Zhou, Jiahang Zhang, Jinfeng Liu, Lin Deng, Wenzhi Li

Background: Successful amelioration of long-term warm ischemia lung injury in donors after cardiac death (DCDs) can remarkably improve outcomes. Hydrogen gas provides potent anti-inflammatory and...

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EFFECT OF ACUTE HYDROGEN-RICH WATER INTAKE ON INTRAOCULAR PRESSURE IN HEALTHY SUBJECTS

E. Najmanova, F. Pluhacek, H. Manethova, M. Botek

Purposes: The primary aim of the study was to assess the response of intraocular pressure (IOP) to the acute ingestion of hydrogen-rich water (HRW) compared...

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Microbial hydrogen economy alleviates colitis by reprogramming colonocyte metabolism and reinforcing intestinal barrier

Bo Shao, Changqing Xu, Jie Qi, Li Ge, Sha Li, Shujing Sui, Shuman Liu, Wengang Song, Xinpei Wu, Xueqiang Sun, Yueran Ren, Zhenzhen Ruan

With the rapid development and high therapeutic efficiency and biosafety of gas-involving theranostics, hydrogen medicine has been particularly outstanding because hydrogen gas (H2), a microbial-derived...

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Molecular hydrogen modulates brain glutamate/GABA-glutamine cycle in overweight humans

Darinka Korovljev, Jelena Ostojic, Nikola Todorovic, Sergej M. Ostojic

Introduction: We evaluated whether 12-week intake of molecular hydrogen (H2) in 5 overweight adults (3 women; age: 50.2 ±11.9 years, body mass index: 29.4 ±2.1...

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