Hydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers

Darinka Korovljev, Dragana Zanini, Jelena Ostojic, Nikola Todorovic, Sergej M. Ostojic, Valdemar Stajer

The main aim of this randomized-controlled cross-over interventional trial was to assess the acute effects of taking a single dose of hydrogen-rich water (HRW), and...

Read Study Article coming soon

Inhalation of 2% Hydrogen Improves Survival Rate and Attenuates Shedding of Vascular Endothelial Glycocalyx in Rats with Heat Stroke

Kensuke Kobayashi, Sang Kien Truong, Soichiro Mimuro, Takasumi Katoh, Tsunehisa Sato, Yoshiki Nakajima

Heat stroke is characterized by excessive oxidative stress and inflammatory responses, both of which are implicated in vascular endothelial glycocalyx shedding and heat-stroke mortality. Although...

Read Study Article coming soon

Colonic lactulose fermentation has no impact on glucagon-like peptide-1 and peptide-YY secretion in healthy young men

Astrid Marie Gauguin, Bolette Hartmann, Charlotte Bayer Christiansen, Jens Juul Holst, Simon Veedfald, Soren Moller, Sten Madsbad, Thomas Moritz

Context: The colon houses most of our gut microbiota, which ferments indigestible carbohydrates. The products of fermentation have been proposed to influence the secretion of...

Read Study Article coming soon

Molecular hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced increases in interleukin-1 alpha and interleukin-6 secretion in human gingival cells

Akira Matsumoto, Daigo Matsuoka, Nene Yonekura, Yasukazu Saitoh

Periodontitis is defined as a multifactorial polymicrobial infection accompanied by inflammatory reactions. Porphyromonas gingivalis (Pg) is known as a major pathogen in the initiation and...

Read Study Article coming soon

Antioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells

Ailyn Fadriquela, Cheol-Su Kim, Huang-Un Kwon, In-Soo You, Jaeyong Sung, Johny Bajgai, Kyu-Jae Lee, Md Habibur Rahman, So-Yeon Lee, Subham Sharma, Thuy Trinh Thi

Oxidative stress plays a crucial role in the development of airway diseases. Recently, hydrogen (H2) gas has been explored for its antioxidant properties. This study...

Read Study Article coming soon

Hydrogen-enriched water eliminates fine particles from the lungs and blood by enhancing phagocytic activity

An E. Suk, E.K. Choi, J. Choi, S.P. Lee, Seo D. Woom, T.S. Kim, Y. Lin, Y.B. Kim, Y.H. Ban

Particulate matters (PM) are one of the major body burdens leading to diseases. We investigated the capacities of a hydrogen-enriched water (HW) eliminating carbon nanoparticles...

Read Study Article coming soon

The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration

Chi-Feng Hung, Der-Chen Chang, Hv-Hui Zong, I-Chia Liang, Pei-Chen Lai, Wen-Chin Ko, Yi-Ru Lin, Yu-Jou Hsu, Yun-Hsiang Chang

Background: Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Choroidal neovascularization (CNV) is the major pathologic feature of neovascular AMD....

Read Study Article coming soon

Hydrogen-Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects in an Acute Ischemia-Reperfusion Injury Mouse Model

Dain Lee, Jong-Il Choi

Background: Cerebral ischemia and its reperfusion injury facilitate serious neurodegenerative diseases such as dementia due to cell death; however, there is currently no treatment for...

Read Study Article coming soon

High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner

Jingwen Li, Junfeng Du, Rongqin Li, Xixin Yan

The aim of this study was to investigate the efficacy and underlying mechanism of high concentration of hydrogen on lipopolysaccharide (LPS)-induced acute lung injury (ALI)....

Read Study Article coming soon

Hydrogen nanobubbles: A novel approach toward radio-sensitization agents

Habib Zaidi, Mahdi Kahani, Ramin Jaberi, Samaneh Hashemi, Seyed Mahmoud-Reza Aghamiri, Zahra Siavashpour

Background: Ocular melanoma is a rare kind of eye malignancy that threatens the patient's eyesight. Radiotherapy and surgical removal are the most commonly used therapeutic...

Read Study Article coming soon

Molecular hydrogen as an adjuvant therapy may be associated with increased oxygen saturation and improved exercise tolerance in a COVID-19 patient

Alexander T. Tarnava, Ghazi Halabi, Ghizal Fatima, Ram B. Singh, Richa H. Rai, Tyler W. LeBaron

Administration of molecular hydrogen dissolved in water to patient with COVID-19-like symptoms may improve oxygen levels and exercise capacity. Publish Year 2021 Country India Rank...

Read Study Article coming soon

Hydrogen Protection Boosts the Bioactivity of Chrysanthemum morifolium Extract in Preventing Palmitate-Induced Endothelial Dysfunction by Restoring MFN2 and Alleviating Oxidative Stress in HAEC Cells

Guanfei Zhang, Jiankang Liu, Lin Zhao, Min Wang, Oumeng Song, Xin Guo, Xuyun Liu, Yilin Gao

As the most important natural antioxidants in plant extracts, polyphenols demonstrate versatile bioactivities and are susceptible to oxidation. The commonly used ultrasonic extraction often causes...

Read Study Article coming soon